Depression
On this page:
The Ottawa Hospital is conducting cutting-edge research to improve our understanding of depression and develop better treatments. This page includes selected news stories about our research related to depression, links to researchers working in this area and related resources. Learn more below.
Research & News
Labs and Groups
These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.
Albert Lab
Chen Lab
Cognitive Health in Multiple Sclerosis Research Lab
Hatching Ideas Lab
Cheryl Harris
Clinician Investigator, Neuroscience
Clinical Trials
The following list of clinical trials at The Ottawa Hospital is pulled from ClinicalTrials.gov, which is hosted by the U.S. National Library of Medicine and only available in English. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. If you email the study team directly, we can guarantee a response. Learn more about participating in research and clinical trials.
PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL) (NCT04754061)
Depression, Anxiety, Distress, Emotional View DetailsSYNCED - SYNChronized Eating in Bipolar Depression Study (NCT06560957)
Bipolar Depression, Bipolar I Disorder, Bipolar II Disorder View DetailsPublications
The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.
Psychedelics for treatment of negative symptoms and depressive symptoms in schizophrenia spectrum disorder: A narrative review.
2026-06-01 Go to publicationA Novel Polygenic Risk Score Indexing Somatostatin-Expressing Inhibitory Neurons Predicts Somatostatin-Expressing Cell Proportions and Severity of Symptoms in Late-Life Depression.
2026-01-02 Go to publicationToward Precision Psychiatry: Using Clinical and Pharmacokinetic Data to Increase Antidepressant Dose or Change Treatment in Late-Life Depression.
2026-04-28 Go to publicationA Decision-Support System to Personalize Antidepressant Treatment in Major Depressive Disorder: A Randomized Clinical Trial.
2026-04-14 Go to publicationSARS-CoV-2 Infection and COVID-19 Vaccine Antibody Responses in Two Canadian Cohorts of Persons Living with HIV.
2026-04-03 Go to publication