Rashmi Kothary

Rashmi Kothary

Ph.D.

Senior Scientist, Regenerative Medicine

Ottawa Hospital Research Institute

Professor, Medicine

University of Ottawa

Professor, Cellular and Molecular Medicine

University of Ottawa

Contact

613-737-8707

Lab Tel: 613-739-6634; Heidi Hickey (Research Administrative Assistant) 613-737-8899 x72794, hhickey@,ohri.ca

Research Groups

Research Group
Kothary Lab
Our laboratory is interested in understanding the mechanisms which maintain/alter muscle and nervous system integrity. In parallel, we are assess...

Bio

Dr. Kothary is a Senior Scientist at the Ottawa Hospital Research Institute (OHRI) and has served as OHRI’s Deputy Scientific Director since 2012. He received a PhD in Biochemistry from the University of British Columbia and pursued postdoctoral research in the laboratories of Dr. Janet Rossant at the Mount Sinai Hospital Research Institute in Toronto and Dr. Azim Surani in Cambridge, U.K. It was during these formative years that Dr. Kothary developed his interests in pre-clinical models to study disease pathology. He has held the University Health Research Chair in Neuromuscular Disorders and is a Professor at the University of Ottawa. His current research focuses on investigating factors important for oligodendrocyte mediated myelination and remyelination of the CNS (in the context of Multiple Sclerosis) and understanding Spinal Muscular Atrophy pathogenesis to identify novel therapeutics for this devastating children’s disease. He currently sits on the SMA Beyond advisory board and on the scientific advisory board for RHU SMART (France), MDA and Cure SMA, and is a reviewer for the CIHR, NIH, Shriners Hospitals, MS Soc, and MDC.


News


Publications

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

2025-02-20 Go to publication

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

2025-02-20 Go to publication

Impact of liver-specific survival motor neuron (SMN) depletion on central nervous system and peripheral tissue pathology

2025-02-10 Go to publication

SMN depletion impairs skeletal muscle formation and maturation in a mouse model of SMA

2025-01-23 Go to publication

Peripheral defects precede neuromuscular pathology in the Smn 2B/− mouse model of spinal muscular atrophy

2024-11-01 Go to publication

Related Research at The Ottawa Hospital