Michele Ardolino
PhD
Senior Scientist, Cancer Research
Ottawa Hospital Research Institute
Assistant Professor, Department of Biochemistry
Microbiology and Immunology
Contact
613-737-8899 ext 77257
Research Groups
Ardolino Cancer Immunology Lab
Bio
As a young student, I found myself amazed by the combination of elegance and efficiency displayed by the immune system. Once I completed my master in Biotechnology, I enthusiastically joined the Immunological Science program at the University of Rome as a Ph.D student. In the laboratory directed by Angela Santoni, I studied how two populations of immune cells, T cells and NK cells, interact with each other in the human system. After graduation, I decided to move to the US for my post-doctoral training, and in 2010 I joined the group of David Raulet at the University of California, Berkeley. In David’s lab, I have investigated the mechanisms that underlie the failure of the immune response to tumors. I received invaluable training in mouse and tumor immunology during my time in the Raulet lab and I became an expert in the immuno-oncology field. In 2016, I was recruited by a joint effort of the University of Ottawa and the Ottawa Hospital Research Institute to lead a group in cancer immunology. My laboratory is interested in understanding the complex interactions between immune cells and tumors to find new ways to harness the immune system against cancer.
News
Publications
Sox10-Deficient Drug-Resistant Melanoma Cells Are Refractory to Oncolytic RNA Viruses
2023-12-29 Go to publicationA New Functional Screening Platform Identifies Colistin Sulfate as an Enhancer of Natural Killer Cell Cytotoxicity
2022-06-08 Go to publicationMuscle-specific deletion of SLK/Stk2 enhances p38 activity and myogenesis in mdx mice
2021-01-01Related Research at The Ottawa Hospital
- Cancer Research Program
- Head and neck cancer
- Soft tissue sarcoma
- Liver cancer
- Blood cancer
- Brain cancer
- Breast cancer
- Cancer
- Colorectal cancer
- Lung cancer
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
- Skin cancer
- Discovery research
- Immunization
- Immunotherapy
- Model organisms
- Molecular and cellular biology
- Translational research
- Transgenic/knockout models
- Cell therapy
- Disease models
- Cancer immunotherapy
- Clinical research