Directory

Cancer

The Ottawa Hospital is conducting cutting-edge research to improve our understanding of cancer and develop better approaches for treatment and prevention. This page includes selected news stories about our cancer research and links to researchers working in this area. Please also visit our Cancer Research Program webpage.


Labs and Groups

These research teams may include multiple scientists, investigators, staff and trainees all working towards a common goal, or they can represent a single scientist and their team.

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Research Group
Addison Cancer Research Lab
Our laboratory focuses on two main themes; 1) the role of the tumour extracellular matrix (ECM) microenvironment in modulating tumour growth and an...
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Research Group
Ardolino Cancer Immunology Lab
Why don't the Killers kill? Understanding the immune system to develop better immunotherapy The immune system is an incredible weapon against...
Research Group
Auer Lab
The Auer Lab makes use of both preclinical and clinical research to understand the mechanisms responsible for the prometastatic effects of surgery ...
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Research Group
Bell Lab
Our research program is directed towards the identification and characterization of novel cancer killing therapeutic viruses that selectively infec...
Research Group
BMC VMF Group
Our group manufactures biologic or ‘living’ drugs, specifically virus-based therapies. The goal of the BMC-VMF is to provide our partners bo...
Research Group
Cook Lab
Treatment options for ovarian cancer are limited, and while tumours often respond to initial treatments, many recur and become resistant to therapy...
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Research Group
Crawley Lab
Chronic hepatitis C virus (HCV) infection is established in 80% of infected individuals and leads to cirrhosis, hepatocellular carcinoma (HCC) and ...
Research Group
Diallo Lab
Our research team is dedicated to exploring and advancing the field of "viral sensitizer" drugs, which enhance cellular susceptibility to viral m...
Research Group
Doug Manuel Lab
Big data, risk assessment tools, population health, health services, epidemiology, artificial intelligence
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Research Group
Gray Lab
The Gray lab has studied the loss of protein homeostasis in aging and age-related diseases such as neurodegeneration and cancer. Our specific focu...
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Research Group
HERO Group (Dr. Thavorn)
Lead by Dr. Kednapa Thavorn, the HERO group's primary fields of research are health economics, health technology assessment and health equity.
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Research Group
LIU Lab
We study fundamental cell cycle mechanisms, cancer, infertility, and inflammatory bowel disease.
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Research Group
Perkins Lab
The Perkins Lab uses bioinformatics and machine learning to answer cutting-edge questions in stem cell and cancer biology. We focus especially on ...
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Research Group
REthinking Clinical Trials
REaCT is a unique research program aimed at improving lives of people with cancer through patient-centred clinical trials.
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Research Group
Urologic Oncology Group
We are a group of physicians and researchers who are passionate about improving patient care in surgical urologic oncology. Please explore our website
Research Group
Vanderhyden Lab
Determining how risk factors contribute to ovarian cancer initiation and progression, single cell analyses and bioinformatics to investigat...
Hesham Abdelbary
Scientist

Hesham Abdelbary

Scientist, Inflammation and Chronic Disease
Christina Addison
Scientist

Christina Addison

Senior Scientist, Cancer Research
Michele Ardolino
Scientist

Michele Ardolino

Senior Scientist, Cancer Research
Harold Atkins
Clinician Investigator

Harold Atkins

Senior Clinician Investigator, Cancer Research
Rebecca Auer
Scientist

Rebecca Auer

Senior Scientist, Cancer Research
John Bell
Scientist

John Bell

Senior Scientist, Cancer Research
Philip Berardi
Clinician Investigator

Philip Berardi

Clinician Investigator, Cancer Research
Mary Beth Bissell
Clinician Investigator

Mary Beth Bissell

Clinician Investigator, Cancer Research
Rodney Breau
Scientist

Rodney Breau

Senior Scientist, Acute Care Research
Marc Carrier
Scientist

Marc Carrier

Senior Scientist, Inflammation and Chronic Disease
Lisa Caulley
Scientist

Lisa Caulley

Associate Scientist, Acute Care Research
Mark Clemons
Scientist

Mark Clemons

Scientist, Cancer Research
David Cook
Scientist

David Cook

Scientist, Cancer Research
Angela Crawley
Scientist

Angela Crawley

Senior Scientist, Inflammation and Chronic Disease
Kristopher Dennis
Clinician Investigator

Kristopher Dennis

Clinician Investigator, Cancer Research
Jean-Simon Diallo
Scientist

Jean-Simon Diallo

Senior Scientist, Cancer Research
Dean Fergusson
Scientist

Dean Fergusson

Senior Scientist, Methodological and Implementation Research
Sebastien Gilbert
Clinician Investigator

Sebastien Gilbert

Clinician Investigator, Acute Care Research
Douglas Gray
Emeritus

Douglas Gray

Senior Scientist Emeritus, Cancer Research
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Clinician Investigator

Cheryl Harris

Clinician Investigator, Neuroscience
Brian Hutton
Scientist

Brian Hutton

Senior Scientist, Methodological and Implementation Research
Shahidul Islam
Clinician Investigator

Shahidul Islam

Clinician Investigator, Cancer Research
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Investigator

Caryn Ito

Senior Investigator, Regenerative Medicine
Natasha Kekre
Scientist

Natasha Kekre

Scientist, Cancer Research
Ran Klein
Clinician Investigator

Ran Klein

Clinician Investigator, Methodological and Implementation Research
Luke Lavallee
Scientist

Luke Lavallee

Scientist, Acute Care Research
Johné Liu
Scientist

Johné Liu

Senior Scientist, Inflammation and Chronic Disease
Ian Lorimer
Scientist

Ian Lorimer

Senior Scientist, Cancer Research
Douglas Manuel
Scientist

Douglas Manuel

Senior Scientist, Methodological and Implementation Research
Michael McBurney
Emeritus

Michael McBurney

Senior Scientist Emeritus, Cancer Research
Matthew McInnes
Scientist

Matthew McInnes

Scientist, Methodological and Implementation Research
Scott Morgan
Clinician Investigator

Scott Morgan

Clinician Investigator, Cancer Research
Carolyn Nessim
Clinician Investigator

Carolyn Nessim

Clinician Investigator, Cancer Research
Robin Parks
Scientist

Robin Parks

Senior Scientist, Regenerative Medicine
Theodore Perkins
Scientist

Theodore Perkins

Senior Scientist, Regenerative Medicine
Patricia Poulin
Scientist

Patricia Poulin

Associate Scientist, Neuroscience
Jennifer Quizi
Investigator

Jennifer Quizi

Investigator, Cancer Research
Marlise Santos
Clinician Investigator

Marlise Santos

Clinician Investigator, Neuroscience
Jean Seely
Clinician Investigator

Jean Seely

Clinician Investigator, Cancer Research
Amirrtha Srikanthan
Clinician Investigator

Amirrtha Srikanthan

Clinician Investigator, Cancer Research
William Stanford
Scientist

William Stanford

Senior Scientist, Regenerative Medicine
Kednapa Thavorn
Scientist

Kednapa Thavorn

Senior Scientist, Methodological and Implementation Research
Rebecca Thornhill
Clinician Investigator

Rebecca Thornhill

Clinician Investigator, Methodological and Implementation Research
Scientist

Eve Tsai

Scientist, Neuroscience
Corey Tsang
Clinician Investigator

Corey Tsang

Clinician Investigator, Cancer Research
Guy Ungerechts
Affiliate

Guy Ungerechts

Affiliate Investigator, Cancer Research
Barbara Vanderhyden
Scientist

Barbara Vanderhyden

Senior Scientist, Cancer Research
Tzu-Fei Wang
Scientist

Tzu-Fei Wang

Scientist, Inflammation and Chronic Disease
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Clinician Investigator

Xiang Wang

Clinician Investigator, Inflammation and Chronic Disease
John Woulfe
Scientist

John Woulfe

Associate Scientist, Neuroscience
Sondos Zayed
Clinician Investigator

Sondos Zayed

Clinician Investigator, Cancer Research

Clinical Trials

The following list of clinical trials at The Ottawa Hospital is pulled from ClinicalTrials.gov, which is hosted by the U.S. National Library of Medicine and only available in English. If you find a clinical trial that interests you, you can bring the information to the next appointment with your care team and ask if you are eligible for the study. If so, they may be able to refer you to the study team. If you email the study team directly, we can guarantee a response. Learn more about participating in research and clinical trials.

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers (NCT04260802)
Cancer, Neoplasms, Metastatic Cancer, Triple Negative Breast Cancer, Gastric Cancer, Cervical Cancer, Ovarian Cancer, Hepatocellular Carcinoma, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Urothelial Neoplasm, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Locally Advanced Solid Tumor, Locally Advanced Malignant Neoplasm, Squamous Cell Carcinoma, Sarcoma, Merkel Cell Carcinoma, Bladder Cancer View Details
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study (NCT05987241)
Muscle Invasive Bladder Urothelial Carcinoma, Muscle Invasive Renal Pelvis Urothelial Carcinoma, Muscle Invasive Ureter Urothelial Carcinoma, Muscle Invasive Urethral Urothelial Carcinoma, Stage II Bladder Urothelial Carcinoma AJCC v6 and v7, Stage III Bladder Urothelial Carcinoma AJCC v6 and v7, Stage IV Bladder Urothelial Carcinoma AJCC v7 View Details

Publications

The following research publications from The Ottawa Hospital are pulled from PubMed, with publication date of 2020 or later. Note that PubMed is hosted by the U.S. National Library of Medicine and is only available in English.

A Multicenter Prospective Cohort Study on the Use of Weight-Adjusted Dalteparin in Patients Over 90 kg With Acute Cancer-Associated Venous Thromboembolism-The WAVe Study.

2026-01-01 Go to publication

Incidence of Local Treatment and Metastasis During Active Surveillance for Patients With a Small Renal Mass in a National Multicenter Prospective Cohort.

2026-01-01 Go to publication

HER2CLIMB-05: A Phase 3 Study of Tucatinib Versus Placebo in Combination with Trastuzumab and Pertuzumab as First-line Maintenance Therapy for HER2+ Metastatic Breast Cancer.

2025-12-10 Go to publication

Predictors of clinically relevant bleeding during extended anticoagulation for cancer-associated venous thromboembolism (API-CAT): a post-hoc analysis of a randomised, non-inferiority trial.

2025-12-06 Go to publication

Safety and efficiency of D-dimer testing in combination with clinical decision rules to exclude pulmonary embolism in patients with cancer: individual patient data meta-analysis.

2025-12-05 Go to publication
View More on PubMed

Resources

Search for clinical trials at The Ottawa Hospital related to this disease or condition.